fig5

Figure 5. MAGEA3 does not activate PDGF, FGF and ANGPT2 in CRC cell lines. (A-C) mRNA levels of PDGF (A), FGF (B), and ANGPT2 (C) in shNC and shMAGEA3 HCT116 cell lines in normoxia and hypoxia & glucose-deprived (Glu(-)) conditions; (D-F) mRNA levels of PDGF (D), FGF (E), and ANGPT2 (F) in HT29 cell lines overexpressing EGFP and MAGEA3 in normoxia and hypoxia & glucose-deprived conditions. ns: no significance, ^*P < 0.05, ^**P < 0.01, ^***P < 0.001, ^****P < 0.0001. shNC: shRNA for negative control; MAGEA3-OE: MAGEA3 overexpression; Glu(-): glucose-deprived; PDGF: Platelet-derived growth factor; FGF: Fibroblast growth factor; ANGPT2: Angiopoietin-2.