fig6

Stimuli-responsive nanomaterials as modulators of cancer stem cell fate: current progress and future perspectives

Figure 6. (A) Schematic illustration of reversing EMT in mesenchymal-type cancer cells via targeting EMT Inducer (CD146) using BPNSs and mild photothermal treatment; (B) Images of MDA-MB-231 cells in height, topography, and modulus channels after mild PTT treatment. Scale bar: 10 μm. Reproduced with permission[103]. Copyright 2022, American Chemical Society. CD: Cluster of differentiation; ERM: Ezrin, Radixin, and Moesin; PTT: photothermal therapy; EMT: epithelial-mesenchymal transition; BPNS: black phosphorus nanosheet; MDA-MB-231:M.D. Anderson-Metastatic Breast-231.