fig9
Figure 9. In vivo biosafety assessment of UCMSC-NVs. (A) Blood routine (n = 3 per group) of mice after different treatments; (B) Biochemical analysis (n = 3 per group) of mice after different treatments; (C) H&E staining of heart, liver, spleen, lung and kidney of mice after different treatments. UCMSC-NVs: Nanovesicles originating from human umbilical cord mesenchymal stem cells; H&E: hematoxylin and eosin; WBC: white blood cells; RBC: red blood cells; HGB: hemoglobin; MCV: mean cell volume; PLT: blood platelets; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; HCT: hematocrit. ALT: alanine transferase; AST: aspartate transferase; CREA: creatinine; BUN: blood urea nitrogen.
