fig13

Preparation and application of porous framework materials for bio-separation

Figure 13. (A) Synthetic routes of Azo-COF and TP COF; (B and E) SEM images of Azo-COF (B) and Tp-COF (E); (C, D, F, G) HRTEM images of Azo-COF (C and D) and Tp-COF (F and G); (H and I) Schematic representation of model proteins separation in vials (H) and COF-based device (I); (J) Proteins separation by the tandem utilization of Azo-COF and Tp-COF: proteins mixture before treatment (1), the supernatant after (1) treated with Azo-COF (2), the supernatant after (2) treated with TpCOF (3), the eluate of Azo-COF (4), and the eluate of Tp-COF (5); (K) Proteins separation by the COF-based device. Proteins mixture before treatment (1), the eluate of Azo-COF-contained filter (2), the eluate of Tp-COF-contained filter (3), and the solution through the COF-based device (4). (A-K) are reprinted with permission from Ref.[119], Copyright © 2022 by Springer Nature. COF: Covalent organic framework; SEM: scanning electron microscope; HRTEM: high-resolution transmission electron microscopy.

Chemical Synthesis
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