fig2
From: Revisiting mechanisms of resistance to immunotherapies in metastatic clear-cell renal-cell carcinoma

Figure 2. Tumor-intrinsic factors and the TME to describe potential mechanisms of resistance to immune therapies[61]. Reprinted with permission from Multidisciplinary Digital Publishing Institute. Abbreviation: TME, tumor microenvironment. Reproduced from[60] under the Creative Commons Agreement License.