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fig4

From:  ATP-binding cassette transporters at the zebrafish blood-brain barrier and the potential utility of the zebrafish as an in vivo model
ATP-binding cassette transporters at the zebrafish blood-brain barrier and the potential utility of the zebrafish as an <i>in vivo </i>model

Figure 4. Zebrafish ABCG2 homologs do not functionally mimic human ABCG2. Three-day cytotoxicity assays were performed with gedatolisib, THZ1, THZ531, mitoxantrone, SN-38, or topotecan on empty-vector-transfected HEK293 cells (Vector), or HEK293 cells that express human ABCG2 (R5), zebrafish Abcg2a (ZF Abcg2a), Abcg2b (ZF Abcg2b), Abcg2c (ZF Abcg2c), or zebrafish Abcg2d (ZF Abcg2d).

Cancer Drug Resistance
ISSN 2578-532X (Online)
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