fig6
From: EGFR signaling promotes resistance to CHK1 inhibitor prexasertib in triple negative breast cancer

Figure 6. EGF stimulation in MDA-231 increased BAD phosphorylation. MDA-231 cells treated with vehicle, 20 nmol/L prexasertib, 50 nmol/L EGF, or both 50 nmol/L EGF and 20 nmol/L prexasertib were examined after 48 h of exposure. AKT: protein kinase B; EGF: epidermal growth factor; EGFR: epidermal growth factor receptor