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From: Cathepsin K: both a likely biomarker and a new therapeutic target in lymphangioleiomyomatosis?
Figure 2. Selective inhibition of the collagenolytic activity of cathepsin K by targeting its exosite. Schematic drawing summarizing the overall strategy to target cathepsin K using exosite-binding inhibitors. CatK: Cathepsin K; TGF: transforming growth factor.
