fig4

Figure 4. The cells which are theoretically available to cell therapy for reinforcement of sclera in pathologic myopia. Fibroblasts and myofibroblasts are scleral cells maintaining scleral biomechanics. Scleral stem cells might be the native stem cell in sclera. MSCs are stromal cells with the abilities of self-renewal and multilineage differentiation. MSCs exert their therapeutic effect by various paracrine growth factors. The media of MSCs also contains growth factors. Therefore, these cells and media can be made into products and delivered to the posterior sclera and fix the sclera. MSCs: Mesenchymal stem cells.