fig3

Figure 3. (A) Mutation frequency (%) of recurrently mutated genes in splenic marginal zone lymphoma (SMZL). The frequency was calculated using a systematically collated database of published mutations and genes are grouped according to affected pathways. Detailed list and description of mutations, including datasets used, can be accessed in the supplementary material from previous published work^[53]. (B) Word cloud of gene symbols that have been found mutated in SMZL. The size of each gene symbol is proportional to the frequency of mutations in SMZL. (C) Lolliplot of NOTCH2, KLF2 and TP53. The figure illustrates a linear protein representing each gene with its respective domains. The height represents the number of variants reported in the literature and circle colour identifies the type of mutation. Data obtained from Jaramillo Oquendo et al.^[53], 2019.