fig6

Figure 6. Interferometric plasmonic microscopy detection of the number of EVs from A549 cell lines binding different surfaces: (A) Illustration of the experiment; (B) EVs binding positive and negatively charged gold surfaces. Positively charged surface shows immobilization effect while negatively charged surface shows bouncing off of EVs; (C) EVs binding PEG and antibody-coated gold Surface. PEG surface shows bouncing off of EVs while antibody-coated surface shows an “adsorb-stay-desorb” procedure. Adaptations with permission^[130], Copyright 2018, National Academy of Sciences. EVs: Extracellular vesicles; PEG: poly(ethylene glycol).