fig8

Figure 8. HFD increases cholesterol levels in WT and AOC3KO mice. Mean ± SEM of eight WT (black columns) and AOC3KO (open columns) mice fed SD and eight mice each for HFD group. Note the change of y-scale in standard diet (SD) groups (A) for total (left) and LDL-cholesterol (right) only, when compared to HFD group (B). The VLDL fraction was not determined on its own but included in total cholesterol. Differences between WT and KO mice significant at: *P < 0.05, **P < 0.01, ***P <0.001. (C) All mice used for the determinations in (A,B) are plotted for cholesterol levels vs. body weight, with the equation of the linear relationship (dotted line) indicated.