fig6

Figure 6. Frequent genetic alterations in Rho GEFs genes in HCC and CCA. The percentage of patients (when ≥ 4%) with genetic alterations for genes from Rho GEF family are shown. The type of these alterations is indicated by the color, as specified in the legend. Mutation data from whole exome sequencing were taken from cBioportal (https://www.cbioportal.org/) from Liver Hepatocellular Carcinoma (TCGA, Firehose Legacy, 442 samples) and Cholangiocarcinoma (TCGA, Firehose Legacy, 51 samples). HCC: Hepatocellular carcinoma; CCA: cholangiocarcinoma.