fig1

Figure 1. Reported mechanisms by which GSK3β promotes (→) the development of osteosarcoma and rhabdomyosarcoma, while suppressing (—|) osteogenesis and skeletal musculogenesis. →: promoting; —|: suppressive; GSK3β: glycogen synthase kinase 3β; NF-κB: nuclear factor kappa-light-chain-enhancer of activated B cells; FOXO1: forkhead box O-subfamily 1; PAX3: paired box 3