fig9

Figure 9. Bubble map with target proteins of resveratrol using STRING software. Human target proteins of resveratrol that were selected from ChEMBL are visualized as a network of predicted associations. The network nodes represent proteins while the edges represent the protein-protein associations. The colored lines represent different types of evidence - Light blue line: curated database; purple line: experimentally determined; green line: neighborhood; red line: gene fusion; blue line: gene co-occurrence; yellow line: text mining; black line: co-expression. The colored nodes demonstrate the pathways. The KEGG pathway table demonstrates the top ten pathways enriched by resveratrol based on a gene list of human target proteins. Neuroactive ligand-receptor interaction appears at the top of the list with the lowest false discovery rate (2.36 × 1042)